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药靶细胞株 > kinase激酶细胞株 > CBP73295AKT1 WT/BaF3

AKT1 WT/BaF3
名称 AKT1 WT/BaF3
型号 CBP73295
报价
特点 AKT1 WT/BaF3,母细胞:BaF3;
冻存条件:90% FBS+10% DMSO;
  • 详细内容

 

CBP73295

I. Introduction

Cell Line Name:

AKT1 WT/BaF3

Host Cell:

Ba/F3

Stability:16 passages

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

 

Mycoplasma Status:

Negative

 
II.Background

AKT1, RAC-alpha serine/threonine-protein kinase, is a ubquitously expressed serine-threonine protein kinase, which regulates a variety of cell functions including, metabolism, growth, angiogenesis, cell proliferation and survival through PI3K signaling in response to extracellular signals (PMID: 23297823, PMID: 26698230). Akt1 mutations are observed in a variety of tumor types (PMID: 23134728), including breast cancer (PMID: 30212483), gastric cancer (PMID: 29714127), salivary carcinoma (PMID: 29682203), and overexpression has been observed in osteosarcoma (PMID: 29762834) and gastric cancer (PMID: 29278885).

 
III. Representative Data

1.WB of AKT1 WT/BaF3

2.Sanger of AKT1 WT/BaF3


 

CBP73295 sanger.png


3. Anti-proliferation assay


CBP73295 fig.jpg


Figure 3. CTG Proliferation Assay of BaF3 AKT1 WT Cells (C2).

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