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药靶细胞株 > kinase激酶细胞株 > CBP73249AXL (Gas6 Dependent)/BaF3

AXL (Gas6 Dependent)/BaF3
名称 AXL (Gas6 Dependent)/BaF3
型号 CBP73249
报价
特点 AXL (Gas6 Dependent)/BaF3,母细胞:BaF3,AXL (TYRO7) 是一种受体酪氨酸激酶,在各种形式的癌症中过度表达,包括乳腺癌、前列腺癌、结肠直肠癌和非小细胞癌。 AXL 过表达已被证明可促进肿瘤进展和转移并降低抗肿瘤免疫反应,使 AXL 成为抗癌治疗的有吸引力的候选者。
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CBP73249
I. Introduction

Cell Line Name:

AXL (Gas6 Dependent)/BaF3

Gene Synonyms:

AXL

Host Cell:

BA/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10% FBS+2 ug/ml puromycin

Mycoplasma Status:

Negative


II.Background
AXL (TYRO7) is a receptor tyrosine kinase that is overexpressed in various forms of cancer, including breast, prostate, colorectal, and non-small cell cancers. AXL overexpression has been shown to encourage tumor progression and metastasis and to decrease the anti-tumor immune response, making AXL an attractive candidate for anticancer therapies.

III. Representative Data

1. Anti-proliferation assay

CBP73249 fig1.png

CBP73249 fig2.jpg


Figure 1. Anti-proliferation assay of three reference compounds on the AXL (Gas6 Dependent)/BaF3 Stable Cell Line.


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