| 名称 | AXL （Gas6 Dependent）/BaF3 |
| 型号 | CBP73249 |
| 报价 |  |
| 特点 | AXL （Gas6 Dependent）/BaF3，母细胞：BaF3，AXL （TYRO7） 是一种受体酪氨酸激酶，在各种形式的癌症中过度表达，包括乳腺癌、前列腺癌、结肠直肠癌和非小细胞癌。 AXL 过表达已被证明可促进肿瘤进展和转移并降低抗肿瘤免疫反应，使 AXL 成为抗癌治疗的有吸引力的候选者。 |
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药靶细胞株 > kinase激酶细胞株 > CBP73249AXL （Gas6 Dependent）/BaF3
- 详细内容
| CBP73249 | |
| I. Introduction | |
Cell Line Name： | AXL (Gas6 Dependent)/BaF3 |
Host Cell: | BA/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10% FBS+2 ug/ml puromycin |
Mycoplasma Status: | Negative |
| II.Background | |
| AXL (TYRO7) is a receptor tyrosine kinase that is overexpressed in various forms of cancer, including breast, prostate, colorectal, and non-small cell cancers. AXL overexpression has been shown to encourage tumor progression and metastasis and to decrease the anti-tumor immune response, making AXL an attractive candidate for anticancer therapies. | |
| III. Representative Data | |
1. Anti-proliferation assay | |
| |
Figure 1. Anti-proliferation assay of three reference compounds on the AXL (Gas6 Dependent)/BaF3 Stable Cell Line. | |
