名称 | CCDC6-RET V804M/BaF3激酶细胞 |
型号 | CBP73216 |
报价 | |
特点 | CCDC6-RET V804M/BaF3激酶细胞 |
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药靶细胞株 > kinase激酶细胞株 > CBP73216CCDC6-RET V804M/BaF3激酶细胞
- 详细内容
CCDC6-RET V804M/BaF3激酶细胞
CBP73216 | |
I. Introduction | |
Cell Line Name: | CCDC6-RET [V804M]/BaF3 |
Host Cell: | BA/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromycin |
Mycoplasma Status: | Negative |
II.Background | |
CCDC6, coiled-coil domain containing 6, has been shown to play a role in the DNA damaging signaling pathway acting as a substrate of ATM (PMID: 17420723). CCDC6 fusions with RET (PMID: 23154560, PMID: 26078337) and BRAF (PMID: 26314551) have been observed in multiple cancer types. | |
III. Representative Data | |
1. CCDC6-RET V804M/BaF3 | |
2. Sanger of CCDC6-RET [V804M]/BaF3 | |
Figure 2. Breakpoint of CCDC6-RET V804M/BaF3 | |
Figure 3. Point mutation of CCDC6-RET V804M/BaF3 | |
3.Anti-proliferation assay | |
Figure 4. CTG Assay for CCDC6-Ret V804M BaF3 Proliferation. |