名称 | CSF3R Q741*/BaF3 |
型号 | CBP73254 |
报价 | |
特点 | CSF3R Q741*/BaF3,母细胞:BaF3,CSF3R,集落刺激因子 3 受体,编码调节骨髓祖细胞增殖和分化的细胞因子受体(PMID:27789332)。 CSF3R 突变常见于慢性中性粒细胞白血病和急性髓系白血病(PMID:23896413,PMID:30348809)。 |
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药靶细胞株 > kinase激酶细胞株 > CBP73254CSF3R Q741*/BaF3
- 详细内容
CBP73254 | |
I. Introduction | |
Cell Line Name: | CSF3R Q741*/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
CSF3R, colony stimulating factor 3 receptor, encodes a cytokine receptor regulating proliferation and differentiation of myeloid progenitor cells (PMID: 27789332). CSF3R mutations commonly occur in chronic neutrophilic leukemia and acute myeloid leukemia (PMID: 23896413, PMID: 30348809). | |
III. Representative Data | |
1.WB of CSF3R Q741*/BaF3 | |
2. Anti-proliferation assay | |
Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R Q741*/BaF3. |