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药靶细胞株 > GPCR细胞株 > CBP71306DRD2/Ga16/HEK293

DRD2/Ga16/HEK293
名称 DRD2/Ga16/HEK293
型号 CBP71306
报价
特点 DRD2/Ga16/HEK293 冻存条件:90% FBS+10% DMSO
  • 详细内容
CBP71306
I. Background

This gene encodes the D2 subtype of the dopamine receptor, which is coupled to Gi subtype of G protein-coupled receptor. This G protein-coupled receptor inhibits adenylyl cyclase activity. In mice, regulation of D2R surface expression by the neuronal calcium sensor-1 (NCS-1) in the dentate gyrus is involved in exploration, synaptic plasticity and memory formation.A recent study has shown a potential role for D2R in retrieval of fear memories in the prelimbic cortex.


II. Introduction
Host Cell:

HEK293

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM+10%FBS+400ug/ml G418
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assays for DRD2 receptor

Transducer:Gi

Ⅲ. Description of Host Cell Line
Organism:Human
Tissue:kidney
Morphology: Epithelial
Growth Properties: Adherent

Ⅳ. Representative Data


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