名称 | mMRGPRB2/Ga15/HEK293 |
型号 | CBP71341 |
报价 | |
特点 | mMRGPRB2/Ga15/HEK293 冻存条件:90% FBS+10% DMSO |
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电话:4008750250
号码:
手机:18066071954
地址:南京市栖霞区纬地路9号
Email: zhangxiangwen@cobioer.com
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- 详细内容
CBP71341 | |
I. Background | |
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. | |
II. Introduction | |
Host Cell: | HEK293 |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | DMEM+10%FBS+400ug/ml G418+ 100 μg/ml Hygromycin B |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assay for mMRGPRB2 receptor |
Transducer: | Gi |
Ⅲ. Description of Host Cell Line | |
Organism: | Human |
Tissue: | kidney |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1. mMRGPRB2/Ga15/HEK293, the EC50 was 1.47μg/ml. |