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药靶细胞株 > GPCR细胞株 > CBP71341mMRGPRB2/Ga15/HEK293

mMRGPRB2/Ga15/HEK293
名称 mMRGPRB2/Ga15/HEK293
型号 CBP71341
报价
特点 mMRGPRB2/Ga15/HEK293 冻存条件:90% FBS+10% DMSO
  • 详细内容
CBP71341
I. Background

Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction.

 
II. Introduction
Host Cell:

HEK293

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM+10%FBS+400ug/ml G418+ 100 μg/ml Hygromycin B
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for mMRGPRB2 receptor

Transducer:Gi
 
Ⅲ. Description of Host Cell Line
Organism:Human
Tissue:kidney
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

CBP71341 钙流数据图.jpg

Figure 1. mMRGPRB2/Ga15/HEK293, the EC50 was 1.47μg/ml.

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