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药靶细胞株 > 免疫治疗细胞株 > CBP74100mouse FCGR2B/CHO

mouse FCGR2B/CHO
名称 mouse FCGR2B/CHO
型号 CBP74100
报价
特点 mouse FCGR2B/CHO,冻存条件:90% FBS+10% DMSO;培养基:F12K+10%FBS+500ug/ml hygromycin
  • 详细内容

 mouse FCGR2B/CHO

CBP74100
I. Background
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
 
II. Description

FCGR2B (FcγRIIb) is a Protein Coding gene. Diseases associated with FCGR2B include Systemic Lupus Erythematosus and Malaria. Among its related pathways are Microglia Activation During Neuroinflammation: Overview and Osteoclast differentiation. Gene Ontology (GO) annotations related to this gene include IgG binding. 

 
III. Introduction
Host Cell:CHO
Expressed gene:FCGR2B(FcγRIIb)
Stability:32 passages
Synonym(s):Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2, Fc fragment of IgG receptor IIb
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+500ug/ml hygromycin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
 
IV. Description of Host Cell Line
Organism:Mouse
Tissue:Ovary
Disease: Hamster Chinese ovary
Morphology: Epitheloid cell
Growth Properties: Adherent
 
Ⅴ. Representative Data

Figure 1.Recombinant CHO cells constitutively expressing FCGR2B(FcγRIIb).

 

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