hIL11 Effector Reporter Cell-南京科佰生物科技有限公司

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联系人：蒋经理
电话：86-25-86880024
号码：86-25-86880024
手机：18066071954
地址：南京市雨花区长虹路222号
Email： duhaitao@cobioer.com

名称	hIL11 Effector Reporter Cell
型号	CBP74114
报价
特点	hIL11 Effector Reporter Cell，冻存条件：90% FBS+10% DMSO；

CBP74114
I. Background
IL-11 is secreted by bone marrow stromal cells (fibroblasts)and is produced also by a number of mesenchymal cells. The IL-11 receptor (alpha chain) utilizes gp130 as its signal transducer, which is also a component of other cytokine receptors. The alpha chain of the IL-11 receptor has been identified independently as Etl2. IL-11 promotes primary and secondary immune responses in vitro and in vivo and modulates antigen-specific antibody reactions. IL-11 promotes the proliferation of IL-6 dependent plasmacytoma cell lines in the presence of neutralizing IL-6 antibodies. IL-11 also stimulates the T-cell dependent development of IgG-secreting B-cells in spleen cell cultures. IL-11 inhibits the differentiation of pre- adipocytes. It induces the synthesis of some acute phase proteins by hepatocytes.

II. Introduction
Expressed gene:	hIL11
Stability:	32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):	IL-11, IL11, Oprelvekin, Interleukin-11
Freeze Medium:	90% FBS+10% DMSO
Culture Medium:	DMEM + 10%FBS+200ug/ml hygromycin+1ug/ml puromycin
Mycoplasma Testing:	Negative
Storage:	Liquid nitrogen
Application(s):	Functional(Report Gene) Assay


III. Representative Data
Figure 1.hIL11 Induced Reporter Activity of hIL11 Effector Reporter Cell.