名称 | SIRPɑ Effector Reporter Cell |
型号 | CBP74122 |
报价 | |
特点 | SIRPɑ Effector Reporter Cell,冻存条件:90% FBS+10% DMSO; |
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电话:4008750250
号码:
手机:18066071954
地址:南京市栖霞区纬地路9号
Email: zhangxiangwen@cobioer.com
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- 详细内容
CBP74122 | |
I. Background | |
SIRP alpha protein, or Signal regulatory proteinalpha (SIRP-α), also known as Tyrosine protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal Avi and His tags, MW 40.3 kDa*. This SIRP alpha protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in higher molecular weight. | |
II. Introduction | |
Expressed gene: | SIRPɑ |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | SIRP alpha protein, sirpa protein, sirp-a protein, SIRPα, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, 71138-1, 71138-2 |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin+300ug/ml hygromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Functional(Report Gene) Assay |
III. Representative Data | |
Figure 1. Dose response of Sirpɑ Blocking Antibodies in SIRPɑ Effector Reporter Cells With CD47+ Target Cells. Figure 2. Dose response of CD47 Blocking Antibody in SIRPɑ Effector Reporter Cells(C11) With CD47+ Target Cells. | |