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药靶细胞株 > 肿瘤免疫细胞株 > CBP74068ICOSL/CHO IO细胞株

ICOSL/CHO IO细胞株
名称 ICOSL/CHO IO细胞株
型号 CBP74068
报价
特点 ICOSL/CHO
  • 详细内容


CBP74068
I. Background
ICOSL is the Ligand for the T-cell-specific cell surface receptor ICOS. When engaged by the ICOSL, the ICOS initiates a costimulatory signal for T-cell proliferation and cytokine production. It also induces B-cell proliferation and differentiation into plasma cells. The ICOS/ICOSL is a major regulator of the adaptive immune responses and also plays an important role in mediating local tissue responses to inflammatory conditions.
II. Description

Recombinant CHO-K1 cells constitutively expressing human ICOSL (also known as human secreted B7 homolog 2 (B7-H2), CD275, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050.

III. Introduction
Host Cell:CHO, Chinese Hamster Ovary
Expressed gene:ICOSL
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):B7 homolog 2, CD275, ICOSL, ICOSLG, B7-related protein (B7RP), B7-H2
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12k+10%FBS+500ug/ml Hygromycin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):This cell line is useful for screening for ICOSL antibodies through flow cytometry, immunocytochemistry or Western blot.
IV. Description of Host Cell Line
Organism:Cricetulus griseus, hamster, Chinese
Tissue:Ovary
Disease: Hamster Chinese ovary
Morphology: Epitheloid cell
Growth Properties: Adherent
Ⅴ. Representative Data

CBP74068.png


Figure 1.Recombinant CHO-cells constitutively expressing human ICOSL.





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