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基因检测标准品 > Fusion > CBP20183RFGFR2(E17)-AHCYL1(E2) Fusion 标准品

FGFR2(E17)-AHCYL1(E2) Fusion 标准品
名称 FGFR2(E17)-AHCYL1(E2) Fusion 标准品
型号 CBP20183R
报价
特点 FGFR2(E17)-AHCYL1(E2) Fusion
  • 详细内容
CBP20183R
FormatRNA
DescriptionFGFR2, fibroblast growth factor receptor 2, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR2 through activating mutations, fusions, and amplification increases cell proliferation and tumorigenesis (PMID: 22508544) and is observed in prostate (PMID: 30761180), breast, lung, uterine, and ovarian cancers (PMID: 29104507), while FGFR2 amplification (PMID: 31076567) and overexpression (PMID: 30662521) is commonly observed in gastric cancer.
  
Technical Data 
Left GeneFGFR2
Left Breakpointchr10:123243212:-
Right GeneAHCYL1
Right Breakpointchr1:110551656:+
Cosmic IDN/A
BufferRNase-free H2O
  
Product Information
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PurityDownload for COA
RNA electrophoresisDownload for COA
Sanger sequencingDownload for COA
Storage-80℃
Expiry12 months from the date of manufacture



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