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基因检测标准品 > Mutation > CBP10527AI-Edigene® NRAS p.G12C Reference Standard Pl

AI-Edigene® NRAS p.G12C Reference Standard Pl
名称 AI-Edigene® NRAS p.G12C Reference Standard Pl
型号 CBP10527
报价
特点 AI-Edigene® NRAS p.G12C Reference Standard Plus
  • 详细内容
 CBP10527
FormatGenomic DNA
DescriptionNRAS G12C is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12C has not been characterized, but can be predicted to confer a loss of function on Nras protein based on the effects of HRAS G12C and KRAS G12C, which result in a loss of response to GTPase-activating proteins, and transformation of cultured cells (PMID: 26037647, PMID: 6092966).
  
Technical Data 
DNA Change:c.34G>T
AA Changep.G12C
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100%
TranscriptNM_002524.5
Cosmic IDCOSM562
Chr position(GRCh37)chr1:115258748
Buffer:Tris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PurityDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10527.png

Storage4℃
Expiry36 months from the date of manufacture

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