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基因检测标准品 > Mutation > CBP10291IDH2 p.R172S Reference Standard 标准品

IDH2 p.R172S Reference Standard 标准品
名称 IDH2 p.R172S Reference Standard 标准品
型号 CBP10291
报价
特点 IDH2 p.R172S Reference Standard
  • 详细内容

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 CBP10291
FormatGenomic DNA
DescriptionIDH2 R172S lies within the active site of the Idh2 protein (PMID: 19228619). R172S confers a gain of function to the Idh2 protein as demonstrated by accumulation 2HG (R(-)-2-hydroxyglutarate), and leads to increased migration in cultured cells (PMID: 23264629, PMID: 27913435).
  
Technical Data 
DNA Changec.516G>T
AA Changep.R172S
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency51.40%
TranscriptENST00000330062
Cosmic IDCOSM34090
Chr position(GRCh37)chr15:90631837
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10291.png

Storage4°C
Expiry36 months from the date of manufacture

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