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基因检测标准品 > Mutation > CBP10515NRAS p.G13V Reference Standard 标准品

NRAS p.G13V Reference Standard 标准品
名称 NRAS p.G13V Reference Standard 标准品
型号 CBP10515
报价
特点 NRAS p.G13V Reference Standard
  • 详细内容
 CBP10515
FormatGenomic DNA
DescriptionNRAS G13V is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G13V has not been characterized, but can be predicted to confer a loss of function on Nras protein based on the effects of HRAS G13V, which results in a loss of response to GTPase-activating proteins, leading to increased GTP-bound Hras in culture (PMID: 24224811).
  
Technical Data 
DNA Changec.38G>T
AA Changep.G13V
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency50%
TranscriptENST00000369535.4
Cosmic IDCOSM574
Chr position(GRCh37)chr1:115258744
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10515.png

Storage4℃
Expiry36 months from the date of manufacture

 

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