名称 | NRAS p.Q61H Reference Standard 标准品 |
型号 | CBP10313 |
报价 | |
特点 | NRAS p.Q61H Reference Standard |
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CBP10313 | |
Format | Genomic DNA |
Description | NRAS Q61H is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). Q61H confers a loss of function to Nras protein as indicated by increased GTP-bound Nras, which leads to increased downstream pathway activation and cell proliferation in cell culture (PMID: 23103856). |
Technical Data | |
DNA Change | c.183A>C |
AA Change | p.Q61H |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000369535 |
Cosmic ID | COSM586 |
Chr position(GRCh37) | chr1:115256528 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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