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基因检测标准品 > Mutation > CBP10313NRAS p.Q61H Reference Standard 标准品

NRAS p.Q61H Reference Standard 标准品
名称 NRAS p.Q61H Reference Standard 标准品
型号 CBP10313
报价
特点 NRAS p.Q61H Reference Standard
  • 详细内容
 CBP10313
FormatGenomic DNA
DescriptionNRAS Q61H is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). Q61H confers a loss of function to Nras protein as indicated by increased GTP-bound Nras, which leads to increased downstream pathway activation and cell proliferation in cell culture (PMID: 23103856).
  
Technical Data 
DNA Changec.183A>C
AA Changep.Q61H
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency50.00%
TranscriptENST00000369535
Cosmic IDCOSM586
Chr position(GRCh37)chr1:115256528
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10313.png

Storage4℃
Expiry36 months from the date of manufacture
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