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基因检测标准品 > Mutation > CBP10319PIK3CA p.H1047R Reference Standard 标准品

PIK3CA p.H1047R Reference Standard 标准品
名称 PIK3CA p.H1047R Reference Standard 标准品
型号 CBP10319
报价
特点 PIK3CA p.H1047R Reference Standard
  • 详细内容

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 CBP10319
FormatGenomic DNA
DescriptionPIK3CA H1047R is a hotspot mutation that lies within the kinase domain of the Pik3ca protein (UniProt.org). H1047R confers a gain of function on the Pik3ca protein as indicated by increased phosphorylation of Akt and Mek1/2, growth factor-independent cell survival, and transformation in cell culture (PMID: 26627007, PMID: 29533785).
  
Technical Data 
DNA Changec.3140A>G
AA Changep.H1047R
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency50.00%
TranscriptNM_006218.1
Cosmic IDCOSM775
Chr position(GRCh37)chr3:178952085
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10319.png

Storage4℃
Expiry36 months from the date of manufacture

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