名称 | PIK3CA p.Q546R Reference Standard 标准品 |
型号 | CBP10325 |
报价 | ![]() |
特点 | PIK3CA p.Q546R Reference Standard |
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CBP10325 | |
Format | Genomic DNA |
Description | PIK3CA Q546R lies within the helical domain of the Pik3ca protein (PMID: 24559118). Q546R has not been biochemically characterized, but is predicted to confer a gain of function to the Pik3ca protein as demonstrated by increased cell survival and transforming ability in cell culture (PMID: 26627007, PMID: 29533785). |
Technical Data | |
DNA Change | c.1637A>G |
AA Change | p.Q546R |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | NM_006218.1 |
Cosmic ID | COSM12459 |
Chr position(GRCh37) | chr3:178936095 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |