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基因检测标准品 > Mutation > CBP10210TP53 p.D281G Reference Standard 标准品

TP53 p.D281G Reference Standard 标准品
名称 TP53 p.D281G Reference Standard 标准品
型号 CBP10210
报价
特点 TP53 p.D281G Reference Standard
  • 详细内容

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 CBP10210
FormatGenomic DNA
DescriptionTP53 D281G lies within the DNA interaction domain of the Tp53 protein (UniProt.org). The functional effect of D281G is conflicting, as it has been reported to decrease transactivation of wild-type Tp53 targets and also confers a gain of function to Tp53, which leads to aberrant gene transcription and cell migration (PMID: 22114072).
  
Technical Data 
DNA Changec.842A>G
AA Changep.D281G
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100%
TranscriptENST00000269305
Cosmic IDCOSM11232
Chr position(GRCh37)chr17:7577096
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencingDownload for COA
Storage4℃
Expiry36 months from the date of manufacture

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