名称 | TP53 p.H214R Reference Standard 标准品 |
型号 | CBP10215 |
报价 | |
特点 | TP53 p.H214R Reference Standard |
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手机:18066071954
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CBP10215 | |
Format | Genomic DNA |
Description | TP53 H214R lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). H214R results in increased IL-6 expression and colony formation compared to wild-type Tp53 in cell culture (PMID: 11920959), and is therefore predicted to confer a gain of function to Tp53. |
Technical Data | |
DNA Change | c.641A>G |
AA Change | p.H214R |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 35.47% |
Transcript | ENST00000269305 |
Cosmic ID | COSM43687 |
Chr position(GRCh37) | chr17:7578208 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |