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药靶细胞株 > kinase激酶细胞株 > CBP73379PDGFRA V658A/BaF3 细胞株

PDGFRA V658A/BaF3 细胞株
名称 PDGFRA V658A/BaF3 细胞株
型号 CBP73379
报价
特点 PDGFRA V658A/BaF3
  • 详细内容
CBP73379
I. Introduction
Cell Line Name:PDGFRA V658A/BaF3
Host Cell:Ba/F3
Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Complete Culture Medium:RPMI-1640+10%FBS+200ng/ml PDGF-BB
Mycoplasma Status:Negative
II.Background

PDGFRA, platelet-derived growth factor receptor alpha, is a receptor tyrosine kinase that activates PI3K/Akt, RAS/MAPK, and JAK/STAT pathways to promote cell proliferation and survival (PMID: 21605429). PDGFRA mutations have been detected in melanoma, AML, peripheral nerve sheath tumors, sarcoma, and neuroendocrine carcinomas (PMID: 23752188, PMID: 20685895), several fusions have also been reported (PMID: 22432087, PMID: 26276769), and amplification has been observed in glioblastoma (PMID: 23438035).

III. Representative Data

1.Sanger of PDGFRA V658A/BaF3

CBP73379 sanger -[V658A]PDGFRA V658A-C8.png

Figure 1. PDGFRA V658A/BaF3 V658A



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