| 名称 | FCGR2B/TCR Activator/CHO |
| 型号 | CBP74096 |
| 报价 |  |
| 特点 | FCGR2B/TCR Activator/CHO，冻存条件：90% FBS+10% DMSO； |
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电话：86-25-86880024
号码：86-25-86880024
手机：18066071954
地址：南京市雨花区长虹路222号
Email： duhaitao@cobioer.com
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FCGR2B/TCR Activator/CHO
| CBP74096 | |
| I. Background | |
| The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. | |
| II. Description | |
FCGR2B (FcγRIIb) is a Protein Coding gene. Diseases associated with FCGR2B include Systemic Lupus Erythematosus and Malaria. Among its related pathways are Microglia Activation During Neuroinflammation: Overview and Osteoclast differentiation. Gene Ontology (GO) annotations related to this gene include IgG binding. | |
| III. Introduction | |
| Host Cell: | CHO |
| Expressed gene: | FCGR2B（FcγRIIb） |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+2ug/ml puromycin+600ug/ml hygromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| IV. Description of Host Cell Line | |
| Organism: | Cricetulus griseus, hamster, Chinese |
| Tissue: | Ovary |
| Disease: | Hamster Chinese ovary |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| Ⅴ. Representative Data | |
Figure 1.Recombinant CHO cells constitutively expressing FCGR2B(FcγRIIb). | |
