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药靶细胞株 > GPCR细胞株 > CBP71358CXCR4/CHO

CXCR4/CHO
名称 CXCR4/CHO
型号 CBP71358
报价
特点 CXCR4/CHO 冻存条件:90% FBS+10% DMSO
  • 详细内容
CBP71358
I. Background

CXCR4 is a receptor for the C-X-C chemokine SDF-1 (Stromal Cell-Derived Factor 1). It is involved in haematopoiesis and cardiac ventricular septum formation, and plays an essential role in vascularization of the gastrointestinal tract, cerebellar development and survival of hippocampal-neuron of central nerve system. CXCR4 also acts as a primary receptor for some HIV-2 isolates and as a co-receptor with CD4 for HIV-1 X4 viruses.


II. Introduction
Host Cell:

CHO

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CXCR4 receptor

Transducer:N/A

Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epithelial
Growth Properties: Adherent

Ⅳ. Representative Data

Figure 1. Human CXCR4 antibody effect on CXCR4/CHO-K1 clone 6.

Figure 2. CXCL 12 effect on CXCR4/CHO-K1 clone 6.






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