名称 | 41BB/CHO |
型号 | CBP74093 |
报价 | |
特点 | 41BB/CHO |
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CBP74093 | |
I. Background | |
Human CD137 (4-1BB; TNFRS9) is an inducible costimulatory molecule that activates T cells. CD137-CD137L mediated signaling has been shown to be important for proliferation, effector functions and survival of T cells. CD137 is also expressed in NK and NKT cells. Antibodies targeting CD137 activation in immune cells have demonstrated potent anti-tumor effects in cancer patients. | |
II. Introduction | |
Host Cell: | CHO |
Expressed gene: | 41BB |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+2ug/ml puromycin |
Storage: | Liquid nitrogen |
Application(s): | Binding Assay,FACS |
III. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Disease: | Hamster Chinese ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
IV. Representative Data | |