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药靶细胞株 > 肿瘤免疫细胞株 > CBP7409341BB/CHO

41BB/CHO
名称 41BB/CHO
型号 CBP74093
报价
特点 41BB/CHO
  • 详细内容

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CBP74093
I. Background
Human CD137 (4-1BB; TNFRS9) is an inducible costimulatory molecule that activates T cells. CD137-CD137L mediated signaling has been shown to be important for proliferation, effector functions and survival of T cells. CD137 is also expressed in NK and NKT cells. Antibodies targeting CD137 activation in immune cells have demonstrated potent anti-tumor effects in cancer patients.
 
II. Introduction
Host Cell:CHO
Expressed gene:41BB
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:

F12K+10%FBS+2ug/ml puromycin

Storage:Liquid nitrogen
Application(s):Binding Assay,FACS
 
III. Description of Host Cell Line
Organism:Hamster 
Tissue:Ovary
Disease: Hamster Chinese ovary
Morphology: Epithelial
Growth Properties: Adherent
 
IV. Representative Data
 
 

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