hGM-CSF Effector Reporter Cell-南京科佰生物科技有限公司

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名称	hGM-CSF Effector Reporter Cell
型号	CBP74149
报价
特点	hGM-CSF Effector Reporter Cell

CBP74149
I. Background
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine stimulating the production of granulocytes and monocytes from bone marrow precursors. GM-CSF had pro-inflammatory functions and is a therapeutic target in autoimmune disease. GM-CSF signals through JAK2/STAT5 and stimulates the expression of STAT5 target genes.

II. Introduction
Expressed gene:	hGM-CSF
Stability:	32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:	90% FBS+10% DMSO
Culture Medium:	RPMI-1640 + 10% FBS +100ug/ml hygromycin+2 ng/ml GM-CSF
Mycoplasma Testing:	Negative
Storage:	Liquid nitrogen
Application(s):	Functional(Report Gene) Assay

III. Representative Data
Figure 1. Dose Response of Recombinant Human GM-CSF in hGM-CSF Effector Reporter Cells (Clone 10). Figure 2. Inhibition of hGM-CSF-induced Reporter Activity by hGM-CSF Neutralizing Antibody in hGM-CSF Effector Reporter Cells (Clone10).