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药靶细胞株 > 肿瘤免疫细胞株 > CBP74149hGM-CSF Effector Reporter Cell

hGM-CSF Effector Reporter Cell
名称 hGM-CSF Effector Reporter Cell
型号 CBP74149
报价
特点 hGM-CSF Effector Reporter Cell
  • 详细内容
CBP74149
I. Background

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine stimulating the production of granulocytes and monocytes from bone marrow precursors. GM-CSF had pro-inflammatory functions and is a therapeutic target in autoimmune disease. GM-CSF signals through JAK2/STAT5 and stimulates the expression of STAT5 target genes.

II. Introduction
Expressed gene:hGM-CSF
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:

RPMI-1640 + 10% FBS +100ug/ml hygromycin+2 ng/ml GM-CSF

Mycoplasma Testing:Negative
Storage:Liquid nitrogen
III. Representative Data

 COBIOER

Figure 1. Dose Response of Recombinant Human GM-CSF in hGM-CSF Effector Reporter Cells (Clone 10).

 COBIOER

Figure 2. Inhibition of hGM-CSF-induced Reporter Activity by hGM-CSF Neutralizing Antibody in hGM-CSF Effector Reporter Cells (Clone10).




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