名称 | AI-Edigene® BRAF p.V600D Reference Standard P |
型号 | CBP10423 |
报价 | |
特点 | AI-Edigene® BRAF p.V600D Reference Standard Plus |
产品搜索
相关文章
联系我们
联系人:蒋经理
电话:4008750250
号码:
手机:18066071954
地址:南京市栖霞区纬地路9号
Email: zhangxiangwen@cobioer.com
电话:4008750250
号码:
手机:18066071954
地址:南京市栖霞区纬地路9号
Email: zhangxiangwen@cobioer.com
产品展示 / PRODUCTS
- 详细内容
CBP10423 | |
Format | Genomic DNA |
Description | BRAF is a member of the RAF family that is activated by members of the Ras family upon growth factor-induced stimulation. Active Ras can induce heterodimerization of cRaf and BRAF and this may explain the observed cooperativity of cRaf and BRaf in cells responding to growth factor signals. Activating mutations in the BRAF gene are present in a large percentage of human malignant melanomas and in a proportion of colon cancers. The vast majority of these mutations result in a valine to glutamic acid change at residue 600 within the activation segment of B-RAF . |
Technical Data | |
DNA Change | c.1799_1800TG>AT |
AA Change | p.V600D |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000288602 |
Cosmic ID | COSM477 |
Chr position(GRCh37) | chr7:140453135_140453136 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
" _ue_custom_node_="true">