名称 | AI-Edigene® NRAS p.G12V Reference Standard Pl |
型号 | CBP10523 |
报价 | |
特点 | AI-Edigene® NRAS p.G12V Reference Standard Plus |
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手机:18066071954
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CBP10523 | |
Format | Genomic DNA |
Description | NRAS G12V is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12V confers a loss of function on Nras protein as indicated by accumulation of GTP-bound Nras, loss of GTPase-activating protein sensitivity, leading to increased downstream pathway activation in cell culture (PMID: 19966803). |
Technical Data | |
DNA Change: | c.35G>T |
AA Change | p.G12V |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | NM_002524.5 |
Cosmic ID | COSM566 |
Chr position(GRCh37) | chr1:115258747 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purity | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |