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基因检测标准品 > Mutation > CBP10541CDK12 p.Q1088* Reference Standard 标准品

CDK12 p.Q1088* Reference Standard 标准品
名称 CDK12 p.Q1088* Reference Standard 标准品
型号 CBP10541
报价
特点 CDK12 p.Q1088* Reference Standard
  • 详细内容
 CBP10541
FormatGenomic DNA
DescriptionCDK12, cyclin dependent kinase 12, is a key regulator of transcription elongation, regulates the expression of genes involved in DNA repair, and is required for the maintenance of genomic stability (PMID: 24554720; PMID: 22012619). Loss and/or inactivation of CDK12 has been commonly observed in many solid tumor types, including prostate (PMID: 29906450, PMID: 31640893), breast, ovarian, endometrial, uterine (PMID: 30104286), and is a likely tumor suppressor (PMID: 30319007).
  
Technical Data 
DNA Change:c.3262C>T
AA Changep.Q1088*
Mutation typeNonsense_Mutation
ZygosityHeterozygous
Allelic Frequency33.33%
TranscriptNM_016507.4
Cosmic IDCOSM472690
Chr position(GRCh37)chr17:37681093
Buffer:Tris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10541.png

Storage4℃
Expiry36 months from the date of manufacture

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