名称 | CREBBP p.L470* Reference Standard 标准品 |
型号 | CBP10558 |
报价 | |
特点 | CREBBP p.L470* Reference Standard |
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电话:4008750250
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手机:18066071954
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Email: zhangxiangwen@cobioer.com
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CBP10558 | |
Format | Genomic DNA |
Description | CREBBP, CREB-binding protein, is an acetyltransferase (PMID: 30181244) that plays a key role in transcription regulation for a number of different genes involved in a variety of cellular processes including proliferation, differentiation, apoptosis, and DNA repair (PMID: 27380996, PMID: 20435671). Expression, mutations and chromosomal translocations of CREBBP have been associated with various human cancers (PMID: 23839013; PMID: 21390130; PMID: 23022987; PMID: 9290955), including glioblastoma, leukemia (PMID: 21390130, PMID: 21390126, PMID: 25423036), and small cell lung cancer (PMID: 30181244). |
Technical Data | |
DNA Change | c.1409del |
AA Change | p.L470* |
Mutation type | Deletion - Frameshift |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | NM_004380.3 |
Cosmic ID | COSM88767 |
Chr position(GRCh37) | chr16:3832851 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |