名称 | MAP2K1 p.Q56P Reference Standard 标准品 |
型号 | CBP10496 |
报价 | 900 |
特点 | MAP2K1 p.Q56P Reference Standard |
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手机:18066071954
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CBP10496 | |
Format | Genomic DNA |
Description | MAP2K1 Q56P does not lie within any known functional domains of the Map2k1 protein (UniProt.org). Q56P confers a gain of function to the Map2k1 protein as indicated by increased kinase activity and the ability to transform cultured cells (PMID: 22327936, PMID: 7651428) and also demonstrates resistance to some Mek and Braf inhibitors (PMID: 29753091). |
Technical Data | |
DNA Change | c.167A>C |
AA Change | p.Q56P |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000307102.9 |
Cosmic ID | COSM1235481 |
Chr position(GRCh37) | chr15:66727451 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |