| 名称 | KRAS G12C-Q99L/BaF3 Kinase |
| 型号 | CBP73374 |
| 报价 |  |
| 特点 | KRAS G12C-Q99L/BaF3，冻存条件：90% FBS+10% DMSO |
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药靶细胞株 > kinase激酶细胞株 > CBP73374KRAS G12C-Q99L/BaF3 Kinase
- 详细内容
| CBP73374 | |
| I. Introduction | |
Cell Line Name： | KRAS G12C-Q99L/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+5ug/ml blasticidin |
Mycoplasma Status: | Negative |
| II.Background | |
KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118). | |
| III. Representative Data | |
1.Sanger of KRAS G12C-Q99L/BaF3
Figure 1. KRAS(NM_033360.4):c.34G>T p.G12C
Figure 2. KRAS(NM_004985.5):c.296A>T p.Q99L | |
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![CBP73374 sanger-G12C [G12C]BaF3-KRAS-G12C-Q99L-C1.jpg](https://img61.chem17.com/gxhpic_a89b1029a6/969b59aaf9fc955b70439a9ba39a43ee4540c9d1a69c9d462d2e3a7167fa098c90b052257c17b9a0.jpg "CBP73374 sanger-G12C [G12C]BaF3-KRAS-G12C-Q99L-C1.jpg")
![CBP73374 sanger-Q99L [Q99L]BaF3-KRAS-G12C-Q99L-C1.jpg](https://img69.chem17.com/gxhpic_a89b1029a6/969b59aaf9fc955b70439a9ba39a43ee412458d50b7631aeb89657396c1b72d7494a27f754fc2e77.jpg "CBP73374 sanger-Q99L [Q99L]BaF3-KRAS-G12C-Q99L-C1.jpg")
