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基因检测标准品 > Mutation > CBP10514AI-Edigene® IDH2 p.R172K Reference Standard P

AI-Edigene® IDH2 p.R172K Reference Standard P
名称 AI-Edigene® IDH2 p.R172K Reference Standard P
型号 CBP10514
报价
特点 AI-Edigene® IDH2 p.R172K Reference Standard Plus
  • 详细内容
 CBP10514
FormatGenomic DNA
DescriptionIDH2 R172K lies within the active site of the Idh2 protein (PMID: 19228619). R172K confers a gain of function to Idh2, as indicated by the increased conversion of alpha-ketoglutarate to the onco-metabolite 2HG (R(-)-2-hydroxyglutarate) in cell culture (PMID: 20171147, PMID: 21326614).
  
Technical Data 
DNA Changec.515G>A
AA Changep.R172K
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100%
TranscriptNM_002168.4
Cosmic IDCOSM33733
Chr position(GRCh37)chr15:90631838
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10514.png

Storage4°C
Expiry36 months from the date of manufacture

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