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基因检测标准品 > Mutation > CBP10522AI-Edigene® NRAS p.G12R Reference Standard Pl

AI-Edigene® NRAS p.G12R Reference Standard Pl
名称 AI-Edigene® NRAS p.G12R Reference Standard Pl
型号 CBP10522
报价
特点 AI-Edigene® NRAS p.G12R Reference Standard Plus
  • 详细内容
 CBP10522
FormatGenomic DNA
DescriptionNRAS G12R is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12R has not been characterized, but can be predicted to confer a loss of function on Nras protein based on the effects of HRAS G12R and NRAS G12R, which results in decreased GTPase activity, activation of downstream pathways, and transformation of cultured cells (PMID: 6092966, PMID: 26037647, PMID: 23455880).
  
Technical Data 
DNA Change:c.34G>C
AA Changep.G12R
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100%
TranscriptNM_002524.5
Cosmic IDCOSM561
Chr position(GRCh37)chr1:115258748
Buffer:Tris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PurityDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10522.png

Storage4℃
Expiry36 months from the date of manufacture

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