| 名称 | APC p.Q1429* Reference Standard | 
| 型号 | CBP10231 | 
| 报价 |  | 
| 特点 | APC p.Q1429* Reference Standard | 
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|  CBP10231 | |
| Format | Genomic DNA | 
| Description | APC Q1429* results in a premature truncation of the Apc protein at amino acid 1429 of 2843 within the Ctnnb1 binding and down-regulation domain of the Apc protein (PMID: 14672538). Q1429* has not been characterized, however Apc truncation mutants downstream of Q1429 are inactivating (PMID: 18199528) thus, Q1429* is predicted to lead to a loss of Apc protein function. | 
| Technical Data | |
| DNA Change | c.4285C>T | 
| AA Change | p.Q1429* | 
| Mutation type | Substitution - Nonsense | 
| Zygosity | Heterozygous | 
| Allelic Frequency | 50.00% | 
| Transcript | ENST00000457016 | 
| Cosmic ID | COSM18836 | 
| Chr position(GRCh37) | chr5:112175576 | 
| Buffer | Tris-EDTA | 
| Product Information | |
| Intended Use | Research Use Only | 
| Unit Size | 1ug | 
| Concentration | Download for COA | 
| Purofication | Download for COA | 
| DNA electrophoresis | Download for COA | 
| Sanger sequencing | Download for COA | 
| Storage | 4℃ | 
| Expiry | 36 months from the date of manufacture | 



