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基因检测标准品 > Mutation > CBP10228APC p.R1114* Reference Standard

APC p.R1114* Reference Standard
名称 APC p.R1114* Reference Standard
型号 CBP10228
报价
特点 APC p.R1114* Reference Standard
  • 详细内容
 CBP10228
FormatGenomic DNA
DescriptionAPC R1114* results in a premature truncation of the Apc protein at amino acid 1114 of 2843 within the Ctnnb1 binding domain of the Apc protein (PMID: 14672538). R1114* has not been characterized, however Apc truncation mutants downstream of R1114 are inactivating (PMID: 18199528) thus, R1114* is predicted to lead to a loss of Apc protein function.
  
Technical Data 
DNA Changec.3340C>T
AA Changep.R1114*
Mutation typeSubstitution - Nonsense
ZygosityHeterozygous
Allelic Frequency33.33%
TranscriptENST00000457016
Cosmic IDCOSM13125
Chr position(GRCh37)chr5:112174631
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10228.png

Storage4℃
Expiry36 months from the date of manufacture

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