名称 | BRAF p.K601N Reference Standard 标准品 |
型号 | CBP10237 |
报价 | 900 |
特点 | BRAF p.K601N Reference Standard |
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手机:18066071954
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CBP10237 | |
Format | Genomic DNA |
Description | BRAF K601N lies within the protein kinase domain of the Braf protein (UniProt.org). K601N confers a gain of function on Braf, as indicated by increased phosphorylation of MEK and ERK in cell in culture (PMID: 24434212) and induction of cell proliferation and cell viability in culture (PMID: 29533785). |
Technical Data | |
DNA Change | c.1803A>T |
AA Change | p.K601N |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000288602 |
Cosmic ID | COSM6265 |
Chr position(GRCh37) | chr7:140453132 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |