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基因检测标准品 > Mutation > CBP10237BRAF p.K601N Reference Standard 标准品

BRAF p.K601N Reference Standard 标准品
名称 BRAF p.K601N Reference Standard 标准品
型号 CBP10237
报价 900
特点 BRAF p.K601N Reference Standard
  • 详细内容


CBP10237
FormatGenomic DNA
DescriptionBRAF K601N lies within the protein kinase domain of the Braf protein (UniProt.org). K601N confers a gain of function on Braf, as indicated by increased phosphorylation of MEK and ERK in cell in culture (PMID: 24434212) and induction of cell proliferation and cell viability in culture (PMID: 29533785).
  
Technical Data 
DNA Changec.1803A>T
AA Changep.K601N
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency50.00%
TranscriptENST00000288602
Cosmic IDCOSM6265
Chr position(GRCh37)chr7:140453132
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10237.jpg

Storage4℃
Expiry36 months from the date of manufacture



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