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基因检测标准品 > Mutation > CBP10275EZH2 p.Y646N Reference Standard 标准品

EZH2 p.Y646N Reference Standard 标准品
名称 EZH2 p.Y646N Reference Standard 标准品
型号 CBP10275
报价
特点 EZH2 p.Y646N Reference Standard
  • 详细内容

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 CBP10275
FormatGenomic DNA
DescriptionEZH2 Y646N (also reported as Y641N) lies within a SET domain of the Ezh2 protein (UniProt.org). Y646N confers a gain of function to the Ezh2 protein, as demonstrated by increased trimethylation at H3K27 (PMID: 22194861) and promotion of tumor growth in cell line derived xenograft models (PMID: 25493630).
  
Technical Data 
DNA Changec.1936T>A
AA Changep.Y646N
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency50.00%
TranscriptENST00000320356
Cosmic IDCOSM37031
Chr position(GRCh37)chr7:148508728
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10275.png

Storage4℃
Expiry36 months from the date of manufacture

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